Can You Take Midol While Breastfeeding + Alternatives

Can You Take Midol While Breastfeeding + Alternatives

While breastfeeding, it is important to make sure any medication you are taking is compatible with breastfeeding. Fortunately, many medications are - but some options are better than others.

Midol is a popular over-the-counter drug used to help manage menstrual cramps, and many breastfeeding women wonder if it will transfer through breast milk. In this article, I’’l discuss the safety of this medication and alternatives to consider. 

Can You Take Midol While Breastfeeding

Any medication taken while breastfeeding may have adverse effects on your child, so it's a good idea to be extra careful with medications. The risk of side effects depends on various factors, including bioavailability, molecular weight, protein binding, and liquid solubility. While you should not take this information as medical advice, hopefully, it will give you some peace of mind regarding using Midol while breastfeeding. Always consult with your healthcare provider for additional questions. Calling the free Infant Risk hotline is also a great option.

Midol is a diuretic and pain reliever that is available in a variety of forms:

  • Midol Bloat Relief containers Pamabrom. 

  • Midol Complete has acetaminophen, pyrilamine, and 60 mg of caffeine. 

  • Midol Complete has acetaminophen, pyrilamine, pamabrom.

Let's look at each of these medications by itself and whether or not they are considered safe for breastfed infants:

Midol Ingredients

Acetaminophen

Acetaminophen is an L1 drug. This designation is given to drugs that are considered to be the highest level of safety and lowest risk of harm associated with it. Acetaminophen is frequently used during pregnancy and breastfeeding. There can be serious side effects to using too much acetaminophen, such as liver damage or kidney damage, but it's generally pretty low risk. 

Pyrilamine

This is an antihistamine that is rated L3 or probably compatible with breastfeeding. With any antihistamine, there are potential risks associated with sedation (of both mom and baby).  In the Infant Risk forum, one of the administrators said, “Pyrilamine is an antihistamine which blocks the H1 receptor. It is used in many over-the-counter products. Antihistamines in this class may cause excitement in children, or sleeplessness. Pyrilamine also has anticholinergic (drying) effects as well. Use of these older antihistamines in pregnant and breastfeeding mothers should be avoided. Use the newer non-sedating antihistamines, such as loratadine or cetirizine.”

Caffeine

Caffeine is L2, which means there is data to suggest there are only small risks to the infant. Caffeine is generally considered acceptable while breastfeeding in moderate amounts and 60 mg shouldn't cause issues with too many infants. However, you should monitor your baby for increased irritability, trouble sleeping, or being more hyperactive ethan normal. 

Pamabrom

Pamabrom is a diuretic, and unfortunately, it is also an L4 drug.  This means that there is data to suggest it may be hazardous; however, in some situations, the pros may outweigh the cons. It contains bromides, which is not considered compatible with breastfeeding. It may also lead to excess fluid loss, which can impact breast milk production. For this reason, I would avoid anything containing Pamabrom. 

After looking at these ingredients, it looks like Midol Complete is the only form of Midol that would be compatible with breastfeeding. If the medication you are looking at contains Pamabrom or Pyrilamine, you should probably avoid it unless otherwise directed by your doctor. Midol Complete does have caffeine, so if you are watching your caffeine intake, that is something else to keep in mind. With most medications, short-term use is probably going to be the best option. 

Taking one Midol most likely won't do anything to your baby or to your milk supply. If you do take one, try and do it right after nursing or pumping, and limit the amount you take in a day. 

Midol Alternatives

midol alternatives while breastfeeding

There are several alternatives to Midol that you might want to consider using while breastfeeding for pain relief. Some of these are over-the-counter (OTC) medicines, while several natural and homeopathic remedies can help manage menstrual discomfort without conventional medication.

Ibuprofen: 

Ibuprofen is one of the most popular over-the-counter pain relievers for menstrual cramps. As a nonsteroidal anti-inflammatory drug (NSAID), it works by reducing the production of prostaglandins, which are hormone-like substances that trigger uterine contractions and pain. For breastfeeding moms, it’s considered safe in standard doses because a very minimal amount transfers through breast milk. Keep in mind that prolonged use (especially at higher dosages) can lead to stomach issues, ulcers, etc. so use this alternative in moderation.

Ginger Tea or Capsules:

Ginger has natural anti-inflammatory and cramp-easing properties, which make it a great, gentle herbal option for easing menstrual cramps and bloating while breastfeeding. Drinking ginger tea can help with digestive discomfort and nausea that sometimes accompany periods, while capsules are a more convenient, concentrated option. Some research even suggests that ginger may be as effective as NSAIDs in reducing period pain for some women, which is why this is one of my top alternatives.

Warm Compress:

Sometimes the simplest options are the best - and that’s where warm compresses are king. Applying heat directly to the lower abdomen increases blood flow, relaxes tense muscles, and may help to interrupt pain signals. A heating pad, warm compress, or even a microwavable rice pack can be used as needed for quick relief. I’m personally a big fan of hot water bottles. They provide continual, direct heat to relax abdominal muscles and improve circulation. Hot water bottles have the added benefit of being portable and affordable, while electric heating pads allow for adjustable temperature control. Both can be used safely alongside other pain relief methods.Many moms find heat just as effective as over-the-counter pain medications for cramps - without side effects.

Magnesium-Rich Foods:

Magnesium plays a key role in muscle and nerve function, and getting enough of it may help ease uterine contractions that cause cramping. Leafy greens (like spinach), nuts, seeds, beans, and dark chocolate are great options to incorporate in your diet. You may also benefit from a supplement, but food-based magnesium is generally best absorbed and safest. There are many different forms of magnesium, so it’s important if you choose to supplement, to consider sources including:

  • Magnesium Glycinate - Gentle on the stomach, well absorbed, and great for calming the nervous system. This is often the top choice for period cramps, tension, and sleep support.

  • Magnesium Citrate - Also well absorbed and can help with cramping, though it may have a mild laxative effect.

  • Magnesium Malate - Known for supporting energy production in the muscles. Some women find it helpful if fatigue accompanies their cramps.

  • Magnesium Chloride (topical sprays or baths) - Absorbs through the skin and may be soothing for muscle aches. Epsom salt baths (magnesium sulfate) are another popular option for full-body relaxation.

This magnesium complex from Just Ingredients is a good option. I also really like Calm Magnesium gummies.

Chamomile or Raspberry Leaf Tea:

Chamomile tea is known for its calming effects and mild anti-inflammatory properties, which may help reduce cramping and support relaxation. Raspberry leaf tea is traditionally used to tone the uterus and can help balance menstrual flow while easing spasms. While research is still limited, many women find these herbal teas to be a soothing, caffeine-free option during their cycle.

Tens Units:

A TENS unit is a small, portable device that delivers gentle electrical pulses through pads placed on the skin. These pulses help block pain signals and stimulate endorphin release, acting as a natural pain reliever. For period cramps, pads are typically placed on the lower abdomen or lower back. TENS units are drug-free, reusable, and increasingly popular for managing menstrual pain at home. I have personally had good success with a home TENS units, and you can find some affordably priced ones on Amazon.

There are many good alternatives to Midol out there that are better options for breastfeeding moms. As with anything, run these recommendations by your health care provider before trying anything.

For more lactation support for your situation, be sure to consider booking a virtual lactation consult with my team. We work worldwide and would LOVE to help you navigate your breastfeeding journey.

Can You Take Midol While Breastfeeding + Alternatives
Katie Clark, IBCLC

Katie Clark is a mom of three boys and IBCLC who specializes in milk supply issues of all kinds. After struggling to breastfeed her second child, Katie found a passion for helping moms find success and joy in their breastfeeding journeys. She has worked in lactation in various forms since 2015 and officially became an IBCLC in 2023. She loves learning and expanding her skills and feels strongly about mom-centered care that focuses on root cause solutions and emotional support. She lives in Colorado with her family and loves sharing the happiness that comes from being a mother.

https://thebreastfeedingmama.com
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